Biodistribution
- Hum Gene Ther. 2003 Jul 20;14(11):1037-48. Safety of interleukin-12 gene therapy against cancer: a murine biodistribution and toxicity study. Imboden M, Shi F, Pugh TD, Freud AG, Thom NJ, Hank JA, Hao Z, Staelin ST, Sondel PM, Mahvi DM.
- Gene Ther. 2004 Oct;11 Suppl 1:S98-S108. Gene transfer vector biodistribution: pivotal safety studies in clinical gene therapy development. Gonin P, Gaillard C.
- Hum Gene Ther. 2005 Jun;16(6):664-77. Evaluation of biodistribution and safety of adenovirus vectors containing group B fibers after intravenous injection into baboons. Ni S, Bernt K, Gaggar A, Li ZY, Kiem HP, Lieber A.
- Virology. 2009 Mar 30;386(1):44-54. Epub 2009 Feb 10. Comparative analysis of vector biodistribution, persistence and gene expression following intravenous delivery of bovine, porcine and human adenoviral vectors in a mouse model. Sharma A, Bangari DS, Tandon M, Pandey A, HogenEsch H, Mittal SK.
- Exp Mol Med. 2011 Oct 31;43(10):580-6. doi: 10.3858/emm.2011.43.10.065. Preclinical studies for pharmacokinetics and biodistribution of Ad-stTRAIL, an adenovirus delivering secretable trimeric TRAIL for gene therapy. Kim CY, Park SH, Jeong M, Kwon OS, Doh H, Kang SH, Robbins PD, Kim BM, Seol DW, Kim BG.
Residual DNA
- Biologicals. 2007 Jun;35(3):211-5. Specific detection of residual CHO host cell DNA by real-time PCR. Nissom PM.
- J Pharm Biomed Anal. 2011 Apr 28;55(1):71-7.Development of a quantitative PCR assay for residual mouse DNA and comparison of four sample purification methods for DNA isolation. Cai H, Gu X, Scanlan MS, Lively CR.
- J Pharm Biomed Anal. 2011 Apr 28;55(1):71-7. Quantitative Detection of Residual E. coli Host Cell DNA by Real-Time PCR. Cai H, Gu X, Scanlan MS, Lively CR.