Jess™ Automated Western Blotting Services

Industry-leading Western blot services for precise protein identification, quantification, and post-translational modification analysis in drug development and manufacturing.

Advanced automated Western blotting with ProteinSimple Jess™ for enhanced accuracy, efficiency, and high-throughput protein characterization.

We have integrated the Jess™ Platform into our suite of analytical tools to enhance our capacity for supporting drug product manufacturing, preclinical GLP, and clinical GLP. Leveraging our years of experience, we provide support in Western blotting assay development, validation, and sample testing to address our clients’ specific needs.

Our Expertise

Protein Expression Analysis: Accurate quantification of biologic drug protein expression levels with Jess™ system.
Potency Assay: Efficient potency assays for process development, enabling relative protein expression quantification.
Protein Identity and Purity Assay: Multi-attribute assays assessing protein identity and purity simultaneously.
Empty/Full Content Ratio: Automated measurement of empty/full AAV capsid content ratios with high sensitivity.
Viral Titer and VP Capsid Protein Ratio Measurements: Precise quantification of VP1, VP2, VP3 capsid proteins and their molar ratios for AAV quality control.
Process-Related Impurities: Sensitive detection of process-related impurities like host cell proteins and residual contaminants.
Vector Analysis: Scalable vector analysis for lentiviral vectors, including titer, identity, purity, and transduction efficiency.
Targeted Protein Degradation Assay: High-throughput targeted protein degradation assays with reproducible quantitative DC50 curve data.

Choose Avance Biosciences for industry-leading Western blot services powered by the advanced ProteinSimple Jess™ platform, delivering unmatched precision, efficiency, and high-throughput protein analysis. With extensive expertise in assay development, validation, and testing, we tailor solutions to support your drug development and manufacturing needs with reliable, regulatory-compliant results.

Our Customers Say…

Your team met the timelines we needed and did exceptional technical work. I will definitely make my management aware that Avance is a very capable partner for our bioanalytical needs.

Bioanalytical Senior Project Manager, California

Avance Biosciences™ (AB) has delivered the Sequencing data in a record time. Very impressive! We have benefited from AB’s hard work and are very grateful for that. AB team should feel proud of themselves. We thank AB team for their support and contributions, much appreciated.

Head of Quality Control, Microbial Manufacturing Service, California

My experience with Avance has been nothing but positive… I will keep sending work your way as I appreciate the attention your team provides and Avance’s creative technical team. See you soon.

Director Individualized Medicines, California

Avance has been the ideal partner in helping Mission Bio and our client,… be the first in the world to GMP qualify our single cell % transduction assay for a lentiviral gene therapy product. Excellent execution on the part of the Avance team. We look forward to more collaborations in the future.

Senior Director, Cell & Gene Therapy Business, California

From the preliminary conclusion of this work, we are already pleased to thank you for your customer-oriented approach and proactive communication in the course of this study. We are happy to see the profound difference in business mindset between your organization and our previous vendor…

Project Manager, Belgium

Thank you so much for successfully completing this important project for us on time. We are very satisfied with the final report and thank you for taking the extra effort to customize the report format. We will definitely use your lab for future projects.

Program Manager, California

It has been a pleasure working with you and your team. The project was carried out to the highest standard and delivered in a timely manner. I will definitely recommend Avance Biosciences™’ services to colleagues and friends.

Senior Scientist, Singapore