Next Generation Sequencing (NGS) has the potential to unlock causative factors from our genetic material. Because of the sheer magnitude, precision and utilizable nature of the output data, a wealth of information will soon be available from studies completed using NGS. Avance Biosciences is offering GMP/GLP next generation DNA Sequencing services using Illumina’s state-of-art MiSeq and HiSeq systems.

Avance Biosciences experienced scientists can execute next-gen DNA and RNA sequencing techniques of all complexities including difficult templates, viral, bacterial and genomic DNA, as well as projects tailored to your needs.

  • Nucleic acids are extracted from your high quality test sample

  • Library is prepared using randomly fragmented DNA, followed by ligation with custom linkers

  • The library is amplified in arrays using clonal amplification methods and PCR to create clonal clusters

  • Arrays are sequenced

  • Data analyses and in-depth data analyses

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MiSeq

MiSeq

The MiSeq system provides up to 5 Mb of output from DNA with an input as low as 10 ng; it is used for small genome sequencing such as bacteria, viruses, and other microbes as well as 16S rRNA amplicon sequencing for microbial identification and metagenomic analysis.

HiSeq

The HiSeq system is utilized for large genomes greater than 5 Mb; it is used to analyze tumors, determine disease causes, select plants and animals for agricultural breeding programs, and find genetic variations among populations.
NextSeq

NextSeq

A fast, flexible high-throughput desktop sequencer enabling a wide range of applications. Data output can be configured based on sample volume and coverage needs. Applications include: whole-genome, exome, and transcriptome sequencing.

When you partner with Avance Biosciences, you gain a CRO partner that is creative, collaborative and dedicated to sound science with a focus on the regulatory requirements our partners require. Contact our technical staff to discuss how we can support you in your project!

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Dedication to Quality

Dedication To Quality

The Avance Biosciences team is committed to strict adherence to CGMP and GLP regulations enacted by the US, European, Japanese, and other international regulatory agencies.

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Extensive Experience

Open Communication

Our team has extensive knowledge and experience working with scientists, QA/QC professionals, and project managers from over 100 pharmaceutical and biotechnology companies and organizations throughout the world.

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Open Communication

Open Communication

Transparency and integrity are two of our core values. Our well-trained, friendly, and professional study directors and project managers strive to complete your projects on-time with open communication channels and to your specifications.

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Cutting Edge Science

Open Communication

Avance Biosciences’ CGMP/GLP compliant genomic and microbial assays make use of the advanced technologies including real-time PCR, ddPCR, Sanger sequencing, next-gen sequencing, Southern blot, and more.

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