Next Generation Sequencing (NGS) has revolutionized genomics research by enabling high-throughput, cost-effective, and rapid sequencing of DNA and RNA. Avance Biosciences™ is proud to offer cutting-edge NGS services using leading platforms, including the Illumina MiSeq and NextSeq 550 for short-read sequencing, and the Oxford Nanopore Technologies MinION and PromethION 2 Solo for long-read sequencing.
Short-Read Sequencing Platforms:
Illumina MiSeq:
The Illumina MiSeq platform is a benchtop sequencer designed for accuracy, speed, and flexibility. Its rapid turnaround time and low error rates make it ideal for small to medium-sized projects such as small genomes, amplicons, targeted panels, and microbial diversity studies.
Applications:
Targeted sequencing for gene panels, exomes, and amplicons
Microbial sequencing for microbiome analysis and infectious disease research
Small genome sequencing for microbial genomes, viral genomes, and bacterial strains
Illumina NextSeq 550:
The Illumina NextSeq 550 platform offers high-throughput sequencing with enhanced scalability and flexibility. Its high data output and seamless integration with Illumina’s bioinformatics solutions for data analysis make it suitable for large-scale projects such as whole-genome, targeted, and RNA sequencing.
Applications:
Whole-genome sequencing for human, animal, and plant genomes
Transcriptome analysis for gene expression profiling and RNA-seq studies
Epigenetics research for DNA methylation analysis and chromatin immunoprecipitation sequencing (ChIP-seq)
Long-Read Sequencing Platforms:
Oxford Nanopore MinION:
The Oxford Nanopore MinION is a portable, real-time sequencer known for its ability to generate long sequencing reads enabling detection of structural variants, gene fusions, and complex genomic regions.
Applications:
De novo genome assembly for organisms with complex genomes
Structural variant detection for understanding genomic rearrangements
Direct RNA sequencing for transcriptome analysis and isoform identification
Oxford Nanopore PromethION 2 Solo:
The Oxford Nanopore PromethION 2 Solo is a high-throughput, scalable long-read sequencer designed for large-scale, comprehensive genome and transcriptome analysis projects.
Applications:
Population genomics for understanding genetic diversity and evolutionary relationships
Epigenome analysis for profiling DNA modifications and chromatin structure
Metagenomics for studying microbial communities and environmental microbiomes
Avance Biosciences™ offers state-of-the-art NGS services using the Illumina MiSeq, NextSeq 550, Oxford Nanopore MinION, and PromethION 2 Solo platforms. Whether you require short-read sequencing for targeted panels or long-read sequencing for comprehensive genome analysis, our experienced team is committed to delivering accurate and reliable results to advance your research goals. Contact us today to learn more about our NGS capabilities and how we can support your genomics projects.
When you partner with Avance Biosciences™, you gain a CRO partner that is creative, collaborative and dedicated to sound science with a focus on the regulatory requirements our partners require. Contact our technical staff to discuss how we can support you in your project!
