Gene Editing On/Off-Target Analysis
Unlock the full potential of your gene editing programs with Avance Biosciences
Meet evolving regulatory standards and ensure the safety and efficacy of your gene editing-based therapies.
CRISPR and other potent gene editing tools empower scientists to enact precise modifications in ex vivo gene editing for cell therapy and in vivo gene therapy, unlocking unparalleled possibilities for addressing genetic disorders.
Are You Prepared?
To meet evolving regulatory standards and ensure the safety and efficacy of gene editing-based therapies, researchers must take proactive measures to detect and mitigate off-target effects. Rigorous on/off-target analysis ensures precise editing, addressing safety concerns and enhancing therapeutic efficacy, paving the way for reliable and successful treatments.
Our Expertise
- In silico Prediction and rhAmpSeq™ Screening
- GUIDE-Seq and iGUIDE Screening
- Amplicon Sequencing Confirmation
- ddPCR Translocation Studies
- Amplicon Sequencing Translocation Analysis
- Custom Assay Development
Improved Gene Editing Analysis with Avance as Your Testing Partner
- Experience: With over 20 years in the industry, our team brings unparalleled expertise to your gene editing projects.
- Regulatory Compliance: We operate in compliance with GLP and GMP guidelines, including Part 11 regulation, ensuring your data stands up to regulatory scrutiny.
- Cutting-Edge Technology: Our use of NGS, ddPCR, and advanced bioinformatics allows for precise and reliable analysis.
- Collaborative Partnership: We work closely with you to develop scientific and operational roadmaps aligned with your research, clinical, and commercial objectives.
Contact Us For More Info
Our Customers Say…
Your team met the timelines we needed and did exceptional technical work. I will definitely make my management aware that Avance is a very capable partner for our bioanalytical needs.
Bioanalytical Senior Project Manager, California
Avance Biosciences™ (AB) has delivered the Sequencing data in a record time. Very impressive! We have benefited from AB’s hard work and are very grateful for that. AB team should feel proud of themselves. We thank AB team for their support and contributions, much appreciated.Head of Quality Control, Microbial Manufacturing Service, California
My experience with Avance has been nothing but positive… I will keep sending work your way as I appreciate the attention your team provides and Avance’s creative technical team. See you soon.Director Individualized Medicines, California
Avance has been the ideal partner in helping Mission Bio and our client,… be the first in the world to GMP qualify our single cell % transduction assay for a lentiviral gene therapy product. Excellent execution on the part of the Avance team. We look forward to more collaborations in the future.
Senior Director, Cell & Gene Therapy Business, California
From the preliminary conclusion of this work, we are already pleased to thank you for your customer-oriented approach and proactive communication in the course of this study. We are happy to see the profound difference in business mindset between your organization and our previous vendor…
Project Manager, Belgium
Thank you so much for successfully completing this important project for us on time. We are very satisfied with the final report and thank you for taking the extra effort to customize the report format. We will definitely use your lab for future projects.
Program Manager, California
It has been a pleasure working with you and your team. The project was carried out to the highest standard and delivered in a timely manner. I will definitely recommend Avance Biosciences™’ services to colleagues and friends.
Senior Scientist, Singapore