LC-MS/MS Services
High-sensitivity LC-MS/MS for small molecules, peptides, proteins, and metabolites, supporting PK/PD, biomarker, and biotherapeutic studies.
Validated, high-throughput workflows for drug characterization, impurity profiling, stability testing, and targeted proteomics with unmatched specificity and compliance.
Avance Biosciences provides advanced LC-MS services to support drug development, biomarker discovery, and biologics characterization. Using state-of-the-art SCIEX Triple Quad™ and TripleTOF™ platforms, we offer comprehensive quantitative and qualitative analysis to accelerate pharmaceutical and biopharmaceutical research. Our experienced scientists specialize in method development, validation, and reproducible data generation, supporting metabolite identification, formulation assessment, and release testing.
Selected LC-MS/MS Services
Bioanalysis of Small Molecules (PK/PD Studies): Quantification of small-molecule drugs in biological samples to support PK/PD, toxicokinetic, and bioavailability studies across all drug development stages.
Metabolite Profiling & Identification (MetID): Comprehensive metabolite analysis to characterize pathways, major/minor metabolites, and metabolic stability in ADME and liver microsome studies.
Targeted Proteomics (Biomarker Verification): Quantification of proteins in biological matrices for biomarker validation, mechanism-of-action studies, and pathway-specific analyses in precision medicine.
Biotherapeutics & Peptide Quantification: Analysis and quantification of therapeutic peptides and proteins, including mAbs and ADCs, for mapping, PTM profiling, degradation, and biosimilarity assessment.
Lipidomics & Metabolomics: Targeted and untargeted lipid/metabolite analyses to study metabolic pathways, biomarkers, toxicometabolomics, and systems biology in preclinical and clinical research.
Toxicology / Reactive Intermediate Screening: Detection and characterization of reactive metabolites and covalent adducts to assess drug reactivity and early toxicological risk.
Contact Us For More Info
Our Customers Say…
Your team met the timelines we needed and did exceptional technical work. I will definitely make my management aware that Avance is a very capable partner for our bioanalytical needs.
Bioanalytical Senior Project Manager, California
Avance Biosciences™ (AB) has delivered the Sequencing data in a record time. Very impressive! We have benefited from AB’s hard work and are very grateful for that. AB team should feel proud of themselves. We thank AB team for their support and contributions, much appreciated.Head of Quality Control, Microbial Manufacturing Service, California
My experience with Avance has been nothing but positive… I will keep sending work your way as I appreciate the attention your team provides and Avance’s creative technical team. See you soon.Director Individualized Medicines, California
Avance has been the ideal partner in helping Mission Bio and our client,… be the first in the world to GMP qualify our single cell % transduction assay for a lentiviral gene therapy product. Excellent execution on the part of the Avance team. We look forward to more collaborations in the future.
Senior Director, Cell & Gene Therapy Business, California
From the preliminary conclusion of this work, we are already pleased to thank you for your customer-oriented approach and proactive communication in the course of this study. We are happy to see the profound difference in business mindset between your organization and our previous vendor…
Project Manager, Belgium
Thank you so much for successfully completing this important project for us on time. We are very satisfied with the final report and thank you for taking the extra effort to customize the report format. We will definitely use your lab for future projects.
Program Manager, California
It has been a pleasure working with you and your team. The project was carried out to the highest standard and delivered in a timely manner. I will definitely recommend Avance Biosciences™’ services to colleagues and friends.
Senior Scientist, Singapore