Flow Cytometry Services
Unlock critical insights into cellular behavior and function with advanced flow cytometry for drug development and manufacturing.
Accurately characterize immune, stem, cancer, and engineered cells to ensure product quality, safety, and efficacy at every development stage.
Avance Biosciences scientific team boasts over several decades of combined experience in flow cytometry assays. With a proven track record in custom assay development, validation, and sample testing, our team excels in providing creative solutions to address our clients’ specific needs, ensuring efficient, sensitive, and reproducible assays. Leveraging the advanced CytoFLEX multicolor flow cytometer and years of our flow cytometry experience, we’re well positioned to support assays in drug product manufacturing, preclinical GLP, and clinical GLP.
Flow Cytometry Applications
Immunophenotyping: Identify and characterize immune cell subsets using surface and intracellular markers for immunology, vaccine development, and immune monitoring.
Cancer Research: Detect and analyze cancer cells, surface markers, DNA content, and apoptosis to assess progression, prognosis, and treatment response.
Cell Cycle Analysis: Measure DNA content to study cell proliferation, growth, and drug effects on cell cycle progression.
Apoptosis Detection: Quantify apoptotic cells using markers like annexin V and propidium iodide to evaluate programmed cell death and cytotoxicity.
Biomarker Discovery: Identify and validate disease biomarkers by analyzing protein and molecule expression for diagnosis and therapeutic targeting.
Minimal Residual Disease (MRD) Detection: Detect MRD in hematological cancers with high sensitivity to evaluate treatment efficacy and relapse risk.
Microbial & Environmental Analysis: Analyze microorganisms in environmental samples to monitor microbial populations, detect pathogens, and assess water quality.
Stem Cell Research: Characterize stem cells and their differentiation status; isolate specific populations for research or therapy.
Pharmacodynamics (PD) Studies: Evaluate drug effects on targeted cells and pathways to support mechanism-of-action studies and therapeutic optimization.
Clinical Diagnostics: Diagnose and monitor diseases like hematologic disorders and immunodeficiencies with rapid, accurate sample analysis.
Functional Assays: Assess cell functions such as cytokine production, phagocytosis, and signaling for both research and clinical use.
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Our Customers Say…
Your team met the timelines we needed and did exceptional technical work. I will definitely make my management aware that Avance is a very capable partner for our bioanalytical needs.
Bioanalytical Senior Project Manager, California
Avance Biosciences™ (AB) has delivered the Sequencing data in a record time. Very impressive! We have benefited from AB’s hard work and are very grateful for that. AB team should feel proud of themselves. We thank AB team for their support and contributions, much appreciated.Head of Quality Control, Microbial Manufacturing Service, California
My experience with Avance has been nothing but positive… I will keep sending work your way as I appreciate the attention your team provides and Avance’s creative technical team. See you soon.Director Individualized Medicines, California
Avance has been the ideal partner in helping Mission Bio and our client,… be the first in the world to GMP qualify our single cell % transduction assay for a lentiviral gene therapy product. Excellent execution on the part of the Avance team. We look forward to more collaborations in the future.
Senior Director, Cell & Gene Therapy Business, California
From the preliminary conclusion of this work, we are already pleased to thank you for your customer-oriented approach and proactive communication in the course of this study. We are happy to see the profound difference in business mindset between your organization and our previous vendor…
Project Manager, Belgium
Thank you so much for successfully completing this important project for us on time. We are very satisfied with the final report and thank you for taking the extra effort to customize the report format. We will definitely use your lab for future projects.
Program Manager, California
It has been a pleasure working with you and your team. The project was carried out to the highest standard and delivered in a timely manner. I will definitely recommend Avance Biosciences™’ services to colleagues and friends.
Senior Scientist, Singapore