Phage Testing for Non-E. coli Cell Banks
The use of a wider range of microbial cells beyond E. coli in biopharma is expanding the potential for novel therapeutics and bioprocesses.
Detecting lytic and lysogenic phages is essential to ensure product safety and prevent production disruptions caused by phage contamination.
Equipped with more than 20 years of experience of testing lytic and lysogenic phage in E coli cell banks, Avance Biosciences team is also skilled in developing and validating novel assays to detect lytic and lysogenic phages in other microbial organisms, such as Salmonella, Staphylococcus, and Streptococcus.
Our Expertise
Assay Development: Identify positive and negative control strains and permissive host strains for phage testing. Develop methods for lysogenic phage induction and plaque testing protocols for lytic phages to ensure accurate detection.
Assay Optimization: Optimize PFUs for quantifiable plaques, standardize bacterial lawn preparation, set incubation conditions for clear plaque visibility, and refine induction conditions for specific strains.
Assay Validation: Develop validation plans for lytic and lysogenic phage detection, validate assay specificity and limit of detection, and prepare custom SOPs for sample testing.
Sample Testing: Test samples using validated methods with a typical turnaround time of less than 2 weeks
Improved Phage Testing with Avance Biosciences
as Your Testing Partner
Optimizing lytic and lysogenic phage assays ensures high sensitivity and specificity, crucial for quality control and regulatory compliance in biologics manufacturing. Contact Avance Biosciences to secure your biologics production with our advanced phage testing services
Contact Us For More Info
Our Customers Say…
Your team met the timelines we needed and did exceptional technical work. I will definitely make my management aware that Avance is a very capable partner for our bioanalytical needs.
Bioanalytical Senior Project Manager, California
Avance Biosciences™ (AB) has delivered the Sequencing data in a record time. Very impressive! We have benefited from AB’s hard work and are very grateful for that. AB team should feel proud of themselves. We thank AB team for their support and contributions, much appreciated.Head of Quality Control, Microbial Manufacturing Service, California
My experience with Avance has been nothing but positive… I will keep sending work your way as I appreciate the attention your team provides and Avance’s creative technical team. See you soon.Director Individualized Medicines, California
Avance has been the ideal partner in helping Mission Bio and our client,… be the first in the world to GMP qualify our single cell % transduction assay for a lentiviral gene therapy product. Excellent execution on the part of the Avance team. We look forward to more collaborations in the future.
Senior Director, Cell & Gene Therapy Business, California
From the preliminary conclusion of this work, we are already pleased to thank you for your customer-oriented approach and proactive communication in the course of this study. We are happy to see the profound difference in business mindset between your organization and our previous vendor…
Project Manager, Belgium
Thank you so much for successfully completing this important project for us on time. We are very satisfied with the final report and thank you for taking the extra effort to customize the report format. We will definitely use your lab for future projects.
Program Manager, California
It has been a pleasure working with you and your team. The project was carried out to the highest standard and delivered in a timely manner. I will definitely recommend Avance Biosciences™’ services to colleagues and friends.
Senior Scientist, Singapore