Biomarker testing
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Biomarker Analysis Services for Clinical Trials

Biomarker testing identifies molecular indicators of disease, helps stratify patients by predicting treatment responses, and improves selection of participants most likely to benefit. It also monitors biomarker levels to gauge treatment efficacy, provides early signs of success, and flags markers linked to adverse effects to support patient safety.

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Biomarker Analysis Services for Clinical Trials

Biomarker testing identifies molecular indicators of disease, helps stratify patients by predicting treatment responses, and improves selection of participants most likely to benefit. It also monitors biomarker levels to gauge treatment efficacy, provides early signs of success, and flags markers linked to adverse effects to support patient safety.

Our Expertise

At Avance Biosciences, we deliver fit‑for‑purpose biomarker analysis for clinical trials across gene expression, genotyping, protein analysis, metabolomics, epigenetics, immunoassays, cytogenetics, flow‑based phenotyping, and microbiome profiling. These platforms translate samples into actionable decisions, from patient stratification and PD response tracking to safety monitoring. (See the table below for methods such as RNA‑seq, ddPCR, ELISA/MSD, LC‑MS/MS, 16S, and metagenomics.)

Biomarker Analysis Services for Clinical Trials

Service

Purpose

Technology

Gene Expression

Predict treatment outcomes, monitor treatment efficacy, and understand disease pathways.

  • RNA sequencing (RNA-seq)

  • Real-time PCR(RT-qPCR)
  • Digital droplet PCR (ddPCR)

Genotyping

Stratify patients based on genetic profiles and predict their responses to therapies.

  • Amplicon Sanger sequencing

  • Amplicon NGS
  • TaqMan assays
  • End-point PCR

Protein Analysis

Identifies biomarkers for monitoring treatment efficacy.

  • Enzyme-linked immunosorbent assay (ELISA)

  • Meso Scale Discovery (MSD)
  • Westen blotting (Jess)
  • Flow Cytometry
  • LC-MS/MS

Metabolomics

Provides insights into metabolic pathways and identifies biomarkers related to disease and treatment response.

  • LC-MS/MS

Epigenetic Analysis

Identifies biomarkers that influence gene expression and disease outcomes.

  • Bisulfite sequencing
  • Methylation-specific PCR

Immunoassays

Identifies biomarkers in immunotherapy and infectious diseases.

  • ELISA
  • MSD
  • Flow Cytometry

Phenotyping

Identify and classify cell types and assess cellular responses to treatments.

  • Flow Cytometry

Microbiomes Analysis

Identifies microbiome-related biomarkers that can impact health and treatment outcomes.

  • 16S rRNA sequencing

  • metagenomic sequencing

Have Questions?

We are dedicated to timely, high-quality service from the start of your project to the finish. Send us a quick message with your questions to find out what Avance can do for you.

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