Next Generation Sequencing (NGS) has the potential to unlock causative factors from our genetic material. Because of the sheer magnitude, precision and utilizable nature of the output data, a wealth of information will soon be available from studies completed using NGS. Avance Biosciences is offering GMP/GLP next generation DNA Sequencing services using Illumina’s state-of-art MiSeq and HiSeq systems.

  • Nucleic acids are extracted from your high quality test sample

  • Library is prepared using randomly fragmented DNA, followed by ligation with custom linkers

  • The library is amplified in arrays using clonal amplification methods and PCR to create clonal clusters

  • Arrays are sequenced

  • Data analyses and in-depth data analyses



Our industry-leading quality system is designed and maintained to support drug and device research and development, GLP pre-clinical trials, cGMP biomanufacturing, and clinical trials.

Avance Biosciences provides biological testing services to support regulatory submission for clients around the world. These services are conducted under the requirements of Good Laboratory Practices and Current Good Manufacturing Practices as promulgated by the U.S. Food and Drug Administration 21 CFR Part 58 and 21 CFR Part 210 and 211, as well as Good Manufacturing Practice according to ICH Q7, where applicable to the laboratory services provided.

We welcome current and potential clients to conduct on-site quality and technical audits. Clients may contact our Quality Unit to schedule a visit.


MiSeq Sequencer

The MiSeq system provides up to 5 Mb of output from DNA with an input as low as 10 ng; it is used for small genome sequencing such as bacteria, viruses, and other microbes as well as 16S rRNA amplicon sequencing for microbial identification and metagenomic analysis.

HiSeq Sequencer

The HiSeq system is utilized for large genomes greater than 5 Mb; it is used to analyze tumors, determine disease causes, select plants and animals for agricultural breeding programs, and find genetic variations among populations.

When you partner with Avance Biosciences, we give you undivided attention, share our experience and knowledge, and respond to your needs in a timely manner. Contact our technical staff to discuss how we can support you in your project!


Dedication to Quality

Dedication To Quality

The Avance Biosciences team is committed to strict adherence to cGMP and GLP regulations enacted by the US, European, Japanese, and other international regulatory agencies.


Extensive Experience

Open Communication

Our team has extensive knowledge and experience working with scientists, QA/QC professionals, and project managers from over 100 pharmaceutical and biotechnology companies and organizations throughout the world.


Open Communication

Open Communication

Transparency and integrity are two of our core values. Our well-trained, friendly, and professional study directors and project managers strive to complete your projects on-time with open communication channels and to your specifications.


Cutting Edge Science

Open Communication

Avance Biosciences’ cGMP/GLP compliant genomic and microbial assays make use of the advanced technologies including real-time PCR, ddPCR, Sanger sequencing, next-gen sequencing, Southern blot, and more.