SNP Genotyping by Real-time QPCR
Avance Biosciences will determine SNPs of targeted genes by conducting allelic discrimination assays using TaqMan® probes. Pre-designed or custom designed assays may be used.
STR/SSR Polymorphism Analysis
Short tandem repeats (STRs) or simple sequence repeats (SSRs) are end-to-end repeats of short sequences (often 2-6 bp in length). Fragment analysis by capillary electrophoresis is offered to analyze sequence variants.
SNPs, insertions and deletions (indels), transitions and transversions, variable number tandem repeats, and homopolymers are evaluated using bidirectional Sanger DNA sequencing.
Targeted genome resequencing and deep sequencing for rare allelic variants are accomplished through next generation sequencing.
Genomics & Biological Services
All Avance Services Include
Experienced scientists functioning as project managers or study directors
Controlled laboratory environment to prevent cross-contamination
Rigorous sample tracking and handling procedures to prevent mistakes and cross-contamination
Methods validated per ICH GLP/GMP guidelines – also research grade testing available
Projects customized and tailored to suit your needs
Independent quality unit assuring regulatory compliance
Transparent process flow and weekly report on project progress
Professional project reports ready for regulatory filing
Fast turn-around time & Competitive pricing