Next-Generation Sequencing (NGS) Center of Excellence

Avance Biosciences’ NGS Center of Excellence is dedicated to delivering high-quality, CGMP/GLP-compliant sequencing solutions to support every stage of biopharmaceutical development, from discovery through clinical validation and testing.

Our mission is to unite advanced sequencing expertise to maximize efficiency, foster innovation, and provide cutting-edge support for drug development and manufacturing, ensuring we stay agile in a rapidly evolving industry.

Next-Gen and Third-Gen Sequencing Platforms

Equipped with leading platforms, including Illumina, PacBio, Oxford Nanopore, Element AVITI™, and 10x Genomics, we offer unmatched expertise in vector characterization, transgene expression, CRISPR analysis, biodistribution, and release testing. Our integrated approach ensures precise, reliable data to accelerate regulatory submissions, enhance product safety, and advance innovative therapies from research through commercialization.

Short-Read Sequencing

Long-Read Sequencing

Illumina MiSeq

Illumina NextSeq 550

Element AVITI

Nanopore MinION

PacBio Vega

Single-Cell Sequencing

NGS Library Automatic Preparation Platforms

10X Genomics Chromium X

Mission Bio Tapestri

Eppendorf epMotion

Tecan Air LIHA 100

Tecan Air LIHA 150

Sequencing Services

DNA Sequencing

RNA Sequencing

Epigenome

Whole Genome Sequencing (WGS)

Poly(A) / Transcriptomics (RNA-seq)

Whole Genome Bisulfite

Exome Sequencing

Total RNA Sequencing

Reduced Representation Bisulfite

Targeted / PCR-based Sequencing

Single-Cell Gene Expression and Immune Profiling

Chromatin Immunoprecipitation (ChIP-seq)

Metagenomic Sequencing

Metatranscriptome Sequencing

RNA Immunoprecipitation

Plasmid/Vector Sequencing

Gene Therapy Vector Sequencing

Enzymatic Methyl

Digital Southern

Isoform Sequencing

Assay for Transposase-Accessible Chromatic (ATAC-Seq)

Integration Site Analysis

Long ncRNA Sequencing

Adventitious Agent Testing

mRNA-Based Therapy

Regulatory-Ready Sequencing

At Avance Biosciences, we’ve built our Next-Generation Sequencing (NGS) Center of Excellence to meet the growing demand for high-quality, regulatory-compliant sequencing in today’s complex biologics development landscape.

Tailored NGS
Workflows

With deep experience supporting gene therapy, vaccine development, cell and gene editing, and biologics manufacturing, we provide tailored NGS workflows that meet stringent GLP and GMP requirements.

Comprehensive NGS Technologies

Our lab infrastructure supports a full suite of NGS technologies—including long-read, short-read, and single-cell sequencing—with validated platforms such as Illumina, PacBio, Oxford Nanopore, 10x Genomics, and Element Biosciences AVITI.

Expert Support from Discovery to Submission

Whether you’re developing a novel therapeutic, optimizing a manufacturing process, or preparing for an FDA submission, Avance Biosciences provides the scientific expertise, cutting-edge technology, and regulatory insight needed to advance your program.

Have Questions?

We are dedicated to timely, high-quality service from the start of your project to the finish. Send us a quick message with your questions to find out what Avance can do for you.