News & Events

4 10, 2019

First CAR T cell therapy targeting B cell-activating factor receptor eradicates blood cancers


From City of Hope by Letisia Marquez The first CAR T cell therapy targeting the B cell-activating factor receptor on cancerous cells eradicated CD19-targeted therapy-resistant human leukemia and lymphoma cells in animal models, according to City of Hope research published today in Science Translational Medicine. The new therapy will be used in [...]

First CAR T cell therapy targeting B cell-activating factor receptor eradicates blood cancers2019-10-22T12:53:12+00:00
19 08, 2019

Join Us At CAR-TCR Summit – Sept 10-13 – Boston, MA


Avance offers CAR T-Cell therapy testing services supporting drug development and manufacturing. Avance Biosciences provides the development, validation and testing services for assays required by regulatory agencies for thorough characterization of manufactured CAR T-cells, and routine monitoring of modified T-cells levels in patients’ blood during the clinical trial or patient treatment phase...

Join Us At CAR-TCR Summit – Sept 10-13 – Boston, MA2019-08-22T11:53:50+00:00
19 06, 2019

Phage Testing of Bacterial Cultures


Regulatory agencies require companies using microbial cell lines that produce products for human use to regularly complete biosafety testing to ensure that cell banks are free of phage contamination. Bacteriophage (phage) is a virus that infects and replicates within bacteria1, basically bacterial predators. One hundred times smaller than a bacterium, phage are found wherever [...]

Phage Testing of Bacterial Cultures2019-06-19T12:08:17+00:00
11 06, 2019

NGS for Biologics Development Support


NGS represents a technological leap that has potential to revolutionize drug discovery and development. Next Generation Sequencing (NGS) has the potential to unlock causative factors from our genetic material. NGS also represents a technological advancement using array-based sequencing that will improve many aspects of scientific research and advance the field of personalized medicine. Because [...]

NGS for Biologics Development Support2019-06-11T12:26:21+00:00
4 06, 2019

Genomic Testing for CAR T-Cell Therapy Development


Chimeric Antigen Receptor T-cell Therapy, CAR-T, is a type of cancer immunotherapy that has gained world-wide interest in recent years, especially after FDA approval of CAR-T treatments for B-cell acute lymphoblastic leukemia and large B-cell non-Hodgkin’s lymphoma.  CAR-T therapy utilizes a genetic modification of a patient’s T-cells to express a target that is specific for [...]

Genomic Testing for CAR T-Cell Therapy Development2019-06-07T11:32:47+00:00
30 10, 2018

Avance Biosciences Completes Successful FDA Inspection


Avance Biosciences, Inc., a leading biological testing company supporting drug development and manufacturing, announced today that its Houston facility was inspected by the U.S. Food and Drug Administration on October 01 through October 04, 2018.  This inspection focused on the firm’s quality management system, operation procedures, and data integrity, as well as various analyses performed [...]

Avance Biosciences Completes Successful FDA Inspection2019-12-17T23:00:45+00:00
16 05, 2018

Digital PCR Services


Digital PCR (dPCR) provides precise and absolute quantification of nucleic acids without a standard curve and without dependence on amplification efficiency.Digital PCR is ultrasensitive; therefore, appropriate for testing allelic variants and targets of low abundance that are below the sensitivity limit of QPCR. It is also very precise, and is a better tool than QPCR when precise determination of the ratio of several nucleic acid sequences is required.

Digital PCR Services2019-05-23T12:03:50+00:00
25 03, 2012

Avance Biosciences Signed MSA


In the week of March 18, 2012, Avance Biosciences entered a Master Service Agreement (MSA) with a global leader in custom biologics manufacturing. Based on this agreement, Avance Biosciences will provide its GMP level Cell Bank Characterization services, including DNA Sequencing, qPCR, Southern blot and other molecular biological methods, to characterize the Master Cell Bank (MCB), Working Cell Bank (WCB), and End of Production Cells (EOPC) submitted by the clients.

Avance Biosciences Signed MSA2019-06-04T12:02:06+00:00
5 07, 2011

New Website – Avance Biosciences Inc.


To Our Esteemed Customers and Friends: We would like to bring to your attention that Avance Biosciences Inc. has been formed by a group of experienced genomic scientists, quality professionals, biotechnology services experts, and enthusiastic investors.  The founders of the company, combined, have more than 100 years of experience in the genomics and biotechnology services [...]

New Website – Avance Biosciences Inc.2018-12-03T12:22:26+00:00