Plasmid and viral vector DNA with hairpins and other secondary structures can be challenging to sequence using traditional Sanger sequencing technology. Sanger sequencing often fails to produce reliable and accurate results for these difficult-to-sequence templates. Any attempt to dissociate difficult secondary structures ultimately destabilizes sequencing primer annealing, leading to failed Sanger sequencing results.
At Avance Biosciences™, we offer advanced and comprehensive NGS ID testing services for viral vectors and plasmids used in gene therapy, vaccine development, and other biopharmaceutical applications. As the first company in the world to introduce Illumina NGS platform in GMP QC environments back in 2012, we are pioneers in applying NGS technology to support drug development and manufacturing. Our NGS ID testing services offer many advantages over traditional methods, including:
Our team of experienced scientists and bioinformaticians is dedicated to providing reliable and high-quality data that can support your product development and regulatory submissions. We adhere to strict GMP quality control standards promulgated by the US FDA and other agencies worldwide to ensure the quality of our NGS ID testing services.
Contact us today to learn more about our NGS ID testing services for viral vectors and plasmids, and how we can help you achieve your QC and regulatory goals.