Plasmid and viral vector DNA with hairpins and other secondary structures can be challenging to sequence using traditional Sanger sequencing technology. Sanger sequencing often fails to produce reliable and accurate results for these difficult-to-sequence templates. Any attempt to dissociate difficult secondary structures ultimately destabilizes sequencing primer annealing, leading to failed Sanger sequencing results.
At Avance Biosciences™, we offer advanced and comprehensive NGS ID testing services for viral vectors and plasmids used in gene therapy, vaccine development, and other biopharmaceutical applications.
The Power of Next Generation Sequencing in Your Research
Advanced NGS Assays – Experience the cutting-edge capabilities of our NGS assays. We leverage the latest advancements in NGS to provide you with detailed and accurate data for your plasmid and viral vector products. As the first company in the world to introduce Illumina NGS platform in GMP QC environments back in 2012, we are pioneers in applying NGS technology to support drug development and manufacturing.
Viral Vector Plasmid Analysis – Our specialized viral vector plasmid analysis using NGS techniques ensures a detailed examination of the genetic components crucial for viral vector production. Trust us for thorough insights into your viral vector plasmids.
Our NGS ID testing services offer many advantages over traditional methods, including:
Rapid turnaround time from sample to data in less than 2 weeks
High coverage for even the most challenging hairpin or high GC regions
High sequence quality with a Q30 quality score
High fidelity results with PCR-free sequencing library preparation
Validated sequencing analysis pipeline compliant with Part 11 regulations
Capable of evaluating viral DNA structural integrity
Capable of detecting potential plasmid contamination
Quality Assurance in Viral Vector Production
Elevate your viral vector production with our quality assurance processes. Our team of experienced scientists and bioinformaticians is dedicated to providing reliable and high-quality data that can support your product development and regulatory submissions. We adhere to strict GMP quality control standards promulgated by the US FDA and other agencies worldwide to ensure the quality of our NGS ID testing services.
Why Choose Our NGS ID Testing Services?
Customized Plasmid NGS Sequencing – No two research projects are the same. Our plasmid NGS sequencing services are customized to suit the unique requirements of your research, ensuring that you receive insights that matter.
Quality Assurance – We provide reliable NGS testing for viral vector production, ensuring that your vectors meet the highest quality standards.
Compliance – We employ state-of-the-art technology to scrutinize and validate the quality of your vectors, meeting the highest industry standards.
Expertise in Gene Vector Testing – Navigate the complexities of gene vector testing with our expert team. We understand the intricacies of vector gene therapy and offer specialized NGS-based testing services to support your research objectives.
Precise Plasmid Sequencing – For plasmid and vector products, precision is non-negotiable. Benefit from our expertise in plasmid sequencing using NGS assays, delivering accurate insights into the structure and composition of your plasmids for optimized vector production.
Excellence in Viral Vector Therapy – Our specialized NGS testing services are tailored for viral vector therapy. Our advanced techniques provide a comprehensive view of viral vectors, ensuring the safety and efficacy of your therapeutic products.
Partner with Us for Research Excellence
At Avance Biosciences™, we bring a new era of accuracy and reliability to your research and development endeavors. Our NGS testing services cater specifically to the dynamic fields of plasmid and viral vector products, ensuring that your gene therapies and vector productions meet the highest standards of quality.
Contact us today to learn more about our NGS testing services for viral vectors and plasmids, and how can help you achieve your QC and regulatory goals.
Plasmid and viral vector DNA with hairpins and other secondary structures can be challenging to sequence using traditional Sanger sequencing technology. Sanger sequencing often fails to produce reliable and accurate results for these difficult-to-sequence templates. Any attempt to dissociate difficult secondary structures ultimately destabilizes sequencing primer annealing, leading to failed Sanger sequencing results.
At Avance Biosciences™, we offer advanced and comprehensive NGS ID testing services for viral vectors and plasmids used in gene therapy, vaccine development, and other biopharmaceutical applications. As the first company in the world to introduce Illumina NGS platform in GMP QC environments back in 2012, we are pioneers in applying NGS technology to support drug development and manufacturing. Our NGS ID testing services offer many advantages over traditional methods, including:
Rapid turnaround time from sample to data in less than 2 weeks
High coverage for even the most challenging hairpin or high GC regions
High sequence quality with a Q30 quality score
High fidelity results with PCR-free sequencing library preparation
Validated sequencing analysis pipeline compliant with Part 11 regulations
Capable of evaluating viral DNA structural integrity
Capable of detecting potential plasmid contamination
Our team of experienced scientists and bioinformaticians is dedicated to providing reliable and high-quality data that can support your product development and regulatory submissions. We adhere to strict GMP quality control standards promulgated by the US FDA and other agencies worldwide to ensure the quality of our NGS ID testing services.
Contact us today to learn more about our NGS ID testing services for viral vectors and plasmids, and how we can help you achieve your QC and regulatory goals.
Our Customers Say…
Avance Biosciences™ (AB) has delivered the Sequencing data in a record time. Very impressive! We have benefited from AB’s hard work and are very grateful for that. AB team should feel proud of themselves. We thank AB team for their support and contributions, much appreciated.
Head of Quality Control, Microbial Manufacturing Service, California
Your team met the timelines we needed and did exceptional technical work. I will definitely make my management aware that Avance is a very capable partner for our bioanalytical needs.
Bioanalytical Senior Project Manager, California
My experience with Avance has been nothing but positive… I will keep sending work your way as I appreciate the attention your team provides and Avance’s creative technical team. See you soon.
Director Individualized Medicines, California
Avance has been the ideal partner in helping Mission Bio and our client,… be the first in the world to GMP qualify our single cell % transduction assay for a lentiviral gene therapy product. Excellent execution on the part of the Avance team. We look forward to more collaborations in the future.
Senior Director, Cell & Gene Therapy Business, California
From the preliminary conclusion of this work, we are already pleased to thank you for your customer-oriented approach and proactive communication in the course of this study. We are happy to see the profound difference in business mindset between your organization and our previous vendor…
Project Manager, Belgium
Thank you so much for successfully completing this important project for us on time. We are very satisfied with the final report and thank you for taking the extra effort to customize the report format. We will definitely use your lab for future projects.
Program Manager, California
It has been a pleasure working with you and your team. The project was carried out to the highest standard and delivered in a timely manner. I will definitely recommend Avance Biosciences™’ services to colleagues and friends.
Senior Scientist, Singapore
When you partner with Avance Biosciences™, you gain a CRO partner that is creative, collaborative and dedicated to sound science with a focus on the regulatory requirements our partners require. Contact our technical staff to discuss how we can support you in your project!
Dedication to Quality
The Avance Biosciences™ team is committed to strict adherence to GLP and CGMP regulations enacted by the US, European, Japanese, and other international regulatory agencies.
Extensive Experience
Our team has extensive knowledge and experience working with scientists, QA/QC professionals, and project managers from over 100 pharmaceutical and biotechnology companies and organizations throughout the world.
Open Communication
Transparency and integrity are two of our core values. Our well-trained, friendly, and professional study directors and project managers strive to complete your projects on-time with open communication channels and to your specifications.
Cutting Edge Science
Avance Biosciences™’ GLP/GMP compliant genomic and microbial assays make use of the advanced technologies including real-time PCR, digital PCR, Sanger sequencing, next generation sequencing, and more.