Issue Date: June 23, 2026
Issued by: Center for Veterinary Medicine
Topic(s): Anthelmintics, Target Animal – Effectiveness
Status: Final
CVM GFI #114 (VICH GL21) Effectiveness of Anthelmintics: Specific Recommendations for Chickens Gallus gallus
The present guidance for chickens was developed by the Working Group established by the International Cooperation on Harmonisation of Technical Requirements for Registration of Veterinary Medicinal Products (VICH), Anthelmintic Guidances, and subsequently revised in 2024. It should be read in conjunction with Guidance for Industry (GFI) #90 (VICH GL7), “Effectiveness of Anthelmintics: General Recommendations,” which should be referred to for discussion of broad aspects for providing pivotal data to demonstrate product anthelmintic effectiveness. The present document is structured similarly to GFI #90/VICH GL7 with the aim of simplicity for readers comparing both documents.The aim of the guidance for chickens is: (1) to be more specific for certain specific issues for chickens not discussed in GFI #90/VICH GL7; (2) to highlight differences with GFI #90/VICH GL7 on effectiveness data recommendations; and (3) to give explanations for disparities with GFI #90/VICH GL7. We recommend that sponsors refer to the pertinent procedures described in detail in other published documents, e.g., World association for the advancement of veterinary parasitology (WAAVP): Second edition of guidelines for evaluating the efficacy of anthelmintics in poultry. Veterinary Parasitology 305: 109711, 2022, and updated versions as they are published. For other poultry, the principles outlined in this guideline should be used where applicable.
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