BPI West 2024

Ensure the Success of Your Biological Drug Development

Avance Provides Assays to Support your Biopharmaceutical Development & Manufacturing

Avance Biosciences™ is a world-leading CRO specializing in GLP & GMP compliant biological assay development, assay validation, and sample testing services in support of biological drug discovery, development and manufacturing.

What We Do:

We offer CGMP/GLP-compliant assay development, assay validation, and sample testing services to ensure strict regulatory compliance and a smooth journey to market.

Cell bank and viral seed characterization assays

  • Microbial assays for bacterial cell bank release, including identity, purity, stability, viability, and phage contamination
  • qPCR and ddPCR for plasmid copy number or inserted gene copy number
  • Sanger sequencing for plasmid and inserted gene sequence verification
  • Next-generation sequencing (NGS) for plasmid and viral genome confirmation
  • Restriction mapping for plasmid evaluation
  • Southern blots for integration site and inserted gene structure analysis
  • NGS for phage ID

DNA sequencing and residual host cell DNA assays for product release

  • Sanger sequencing for plasmid drug products and viral vaccines
  • NGS for inverted terminal repeats (ITR), GC-rich, and other challenging constructs
  • cDNA sequencing and qPCR for multi-valent RNA vaccines
  • qPCR residual host cell DNA testing for protein drug products

CAR-T and other gene or cell therapy product release

  • Replication competent lentivirus (RCL) and vector copy number (VCN) testing
  • qPCR and ddPCR assays for integrated gene copy analysis
  • NGS amplicon sequencing for product characterization
  • Potency and infectivity assays
  • Transfection assay via single-cell NGS
  • Transfection assay via colony picking and Sanger sequencing
  • STEMvision for colony-forming unit (CFU) assays

Who We Are:

We are a team of dedicated scientists, and quality control professionals focused on meeting your needs and completing your challenging drug development and manufacturing projects.

When you partner with Avance Biosciences™, we give you undivided attention, share our experience and knowledge, and respond to your needs in a timely manner. Contact our technical staff to discuss how we can support you in your project!


We look forward to meeting you at this year’s event!

If you need a specific assay to advance your drug development and/or manufacturing initiatives, please stop by our booth to discuss how we can help.

When you partner with Avance Biosciences™, you gain a CRO partner that is creative, collaborative and dedicated to sound science with a focus on the regulatory requirements our partners require. Contact our technical staff to discuss how we can support you in your project!