WRIB 2024

Ensure the Success of Your Biological Drug Development

Avance Provides Assays to Support your Biopharmaceutical Development & Manufacturing

Avance Biosciences™ is a world-leading CRO specializing in GLP & GMP compliant biological assay development, assay validation, and sample testing services in support of biological drug discovery, development and manufacturing.

What We Do:

We offer CGMP/GLP-compliant assay development, assay validation, and sample testing services to ensure strict regulatory compliance and a smooth journey to market.

Cell bank and viral seed characterization assays

  • Microbial assays for bacterial cell bank release, including identity, purity, stability, viability, and phage contamination
  • qPCR and ddPCR for plasmid copy number or inserted gene copy number
  • Sanger sequencing for plasmid and inserted gene sequence verification
  • Next-generation sequencing (NGS) for plasmid and viral genome confirmation
  • Restriction mapping for plasmid evaluation
  • Southern blots for integration site and inserted gene structure analysis
  • NGS for phage ID

DNA sequencing and residual host cell DNA assays for product release

  • Sanger sequencing for plasmid drug products and viral vaccines
  • NGS for inverted terminal repeats (ITR), GC-rich, and other challenging constructs
  • cDNA sequencing and qPCR for multi-valent RNA vaccines
  • qPCR residual host cell DNA testing for protein drug products

CAR-T and other gene or cell therapy product release

  • Replication competent lentivirus (RCL) and vector copy number (VCN) testing
  • qPCR and ddPCR assays for integrated gene copy analysis
  • NGS amplicon sequencing for product characterization
  • Potency and infectivity assays
  • Transfection assay via single-cell NGS
  • Transfection assay via colony picking and Sanger sequencing
  • STEMvision for colony-forming unit (CFU) assays

Who We Are:

We are a team of dedicated scientists, and quality control professionals focused on meeting your needs and completing your challenging drug development and manufacturing projects.

When you partner with Avance Biosciences™, we give you undivided attention, share our experience and knowledge, and respond to your needs in a timely manner. Contact our technical staff to discuss how we can support you in your project!

WRIB Floorplan

We look forward to meeting you at this year’s event!

If you need a specific assay to advance your drug development and/or manufacturing initiatives, please stop by our booth to discuss how we can help.

When you partner with Avance Biosciences™, you gain a CRO partner that is creative, collaborative and dedicated to sound science with a focus on the regulatory requirements our partners require. Contact our technical staff to discuss how we can support you in your project!