From Basic Research Through GMP Commercial Manufacturing, Avance Biosciences™ is Your Trusted Biological Assay Services Partner

Avance Biosciences™ is a leading genomics services company specializing in DNA sequencing, real-time quantitative PCR, next generation sequencing, and many other molecular biology laboratory services. All services are offered either at research grade or in compliance with Good Laboratory Practice (GLP) and current Good Manufacturing Practice (GMP) promulgated by the US FDA, OECD, European Commission (EC), Japanese, and other international regulatory agencies.

DNA/RNA Sequencing

Avance Biosciences™ is a leading genomic service company offering DNA sequencing services to researchers around the world. Our DNA sequencing services include a broad range of offerings that meet your needs, whether you are engaged in basic genomics research or in biological drug development and manufacturing.

Real-Time PCR Analysis

Avance Biosciences™ can perform a broad range qPCR assays using TaqMan® probes. Customers can select established real-time qPCR assays from Avance Biosciences™’ assay list or from the Applied Biosystems website. Assay development, including assay design, validation, transfer and testing is also available.

Genotyping Analysis

Avance Biosciences™ provides a number of genotyping services based on state-of-the-art variant detection and SNP genotyping technologies. These services are offered both at the research grade level and under GLP or GMP regulations to support basic genomics research, drug development, and drug manufacturing.

Gene Expression Analysis

 Avance Biosciences™ meets our customers’ requirements in gene expression accuracy and thoroughput using pre-designed, custom designed, and validated real-time qPCR assays in various formats, as well as the RNA-Seq method using the next generation sequencing platform.

Copy Number Variation

 Avance Biosciences™ can confirm that the copy number of expressing cell banks, whether the cell bank is integrated (the transgene is integrated into the host cell genome), or the cell bank is non-integrated (the expression construct is on an extrachromosomal DNA, typically a plasmid).

Residual DNA Assays

Avance Biosciences™ has developed a number of accurate and sensitive target-specific QPCR assays to detect residual host cell DNA in biopharmaceutical products from a number of common host cell lines (E. coli, CHO cells, and yeast).

Southern / Northern Blotting

Avance Biosciences™ provides all necessary expertise for Southern or Northern blot projects from nucleotide extraction to probe design. We offer Southern blot analysis to support gene discovery and confirmation, gene mapping, evolution and development studies, diagnostics, and forensics tests.

Microbiology Services

Regulatory agencies require microbial cell bank manufacturers to ensure continued stability and safety of cell lines that produce products for human use. Avance Biosciences™ offers comprehensive services for bacterial cell lines at all stages of production under GLP/GMP regulatory compliance.

Regulatory Level Services

All services are offered either at research grade or in compliance with Good Laboratory Practice (GLP) and current Good Manufacturing Practice (GMP) promulgated by the US FDA, OECD, European Commission (EC), Japanese, and other international regulatory agencies.

GMP Level Regulatory Services

CGMP (Current Good Manufacturing Practices) are the practices required in order to conform to the guidelines recommended by agencies that control the authorization and licensing of the manufacture and sale of pharmaceutical products, and medical devices.

GLP Regulatory Level Services

GLP (Good Laboratory Practice) ensures scientific data integrity is being protected at the research level and is applicable for experimental or non-clinical studies conducted for the assessment of the safety or efficacy.

Research & Discovery Level Services

Any of our services are also available at research level with a reduced cost. Research level testing is completed without quality assurance oversight and is not appropriate for submission to regulatory agencies.

Have questions?

We are dedicated to timely, high-quality service from the start of your project to the finish. Send us a note or give us a call to find out what Avance can do for you.

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Ready to get started?

Give us a little background on your needs and the goals of your project, and we’ll send a preliminary quote including: tasks, deliverables and a no-obligation cost estimate.

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Our Customers Say…

Avance Biosciences™ (AB) has delivered the Sequencing data in a record time. Very impressive! We have benefited from AB’s hard work and are very grateful for that. AB team should feel proud of themselves. We thank AB team for their support and contributions, much appreciated.

Head of Quality Control, Microbial Manufacturing Service, California

Your team met the timelines we needed and did exceptional technical work. I will definitely make my management aware that Avance is a very capable partner for our bioanalytical needs.

Bioanalytical Senior Project Manager,  California

My experience with Avance has been nothing but positive… I will keep sending work your way as I appreciate the attention your team provides and Avance’s creative technical team. See you soon.

Director Individualized Medicines,  California

Avance has been the ideal partner in helping Mission Bio and our client,… be the first in the world to GMP qualify our single cell % transduction assay for a lentiviral gene therapy product. Excellent execution on the part of the Avance team. We look forward to more collaborations in the future.

Senior Director, Cell & Gene Therapy Business,  California

From the preliminary conclusion of this work, we are already pleased to thank you for your customer-oriented approach and proactive communication in the course of this study. We are happy to see the profound difference in business mindset between your organization and our previous vendor…

Project Manager, Belgium

Thank you so much for successfully completing this important project for us on time. We are very satisfied with the final report and thank you for taking the extra effort to customize the report format. We will definitely use your lab for future projects.

Program Manager, California

It has been a pleasure working with you and your team. The project was carried out to the highest standard and delivered in a timely manner. I will definitely recommend Avance Biosciences™’ services to colleagues and friends.

Senior Scientist, Singapore

When you partner with Avance Biosciences™, you gain a CRO partner that is creative, collaborative and dedicated to sound science with a focus on the regulatory requirements our partners require. Contact our technical staff to discuss how we can support you in your project!

Partner

Dedication to Quality

Dedication To Quality

The Avance Biosciences™ team is committed to strict adherence to CGMP and GLP regulations enacted by the US, European, Japanese, and other international regulatory agencies.

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Extensive Experience

Open Communication

Our team has extensive knowledge and experience working with scientists, QA/QC professionals, and project managers from over 100 pharmaceutical and biotechnology companies and organizations throughout the world.

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Open Communication

Open Communication

Transparency and integrity are two of our core values. Our well-trained, friendly, and professional study directors and project managers strive to complete your projects on-time with open communication channels and to your specifications.

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Cutting Edge Science

Open Communication

Avance Biosciences™’ CGMP/GLP compliant genomic and microbial assays make use of the advanced technologies including real-time PCR, ddPCR, Sanger sequencing, next-gen sequencing, Southern blot, and more.

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