Avance Biosciences™ offers Sanger sequencing to support our clients worldwide for their drug development and manufacturing activities. The FDA continues to require the completion of two-fold double stranded Sanger sequencing for genomic identity of biologics produced from cell lines via integrated or non-integrated vectors. Avance Biosciences™ experienced scientists can execute DNA sequencing techniques of all complexities including difficult templates, viral, bacterial and genomic DNA, as well as projects tailored to your needs

Plasmid DNAs are separated from cells and used as sequencing template to delineate the sequence of either the whole plasmid or that of a gene(s) of interest.
Amplicon Sequencing PCR products of same gene(s) of interest on a cohort of samples are generated, purified, and sequenced. After analysis, sequence variations, such as SNPs, can be reported.
mRNA/cDNA Sequencing RNA extracted from cell or tissue will be converted to cDNA, PCR amplified and sequenced for the purpose of verifying expressed transcript of a gene(s) of interest
Shotgun Sequencing Genomic DNA, or any DNA of large length, is randomly fragmented and then sub-cloned into a cloning vector. The subclones are random picked and sequenced. The sequence reads are then assembled to form contigs.
Primer-Walking DNA sequencing is delineated through iterative rounds of primer design and sequencing.
Viral DNA/RNA Sequencing Viral DNAs or RNAs are separated from viral particles followed by PCR or RT-PCR before sequencing reactions are performed.

CGMP/GLP Compliant
Genomics & Biological Services

  • Experienced scientists functioning as project managers or study directors
  • Independent quality unit assuring regulatory compliance
  • Methods validated per ICH GLP/GMP guidelines – also research grade testing available
  • Rigorous sample tracking and handling procedures to prevent mistakes and cross-contamination
  • Controlled laboratory environment to prevent cross-contamination

Have questions?

We are dedicated to timely, high-quality service from the start of your project to the finish. Send us a note or give us a call to find out what Avance can do for you.


Ready to get started?

Give us a little background on your needs and the goals of your project, and we’ll send a preliminary quote including: tasks, deliverables and a no-obligation cost estimate.


Our Customers Say…

From the preliminary conclusion of this work, we are already pleased to thank you for your customer-oriented approach and proactive communication in the course of this study. We are happy to see the profound difference in business mindset between your organization and our previous vendor…

Project Manager, Belgium

Thank you so much for successfully completing this important project for us on time. We are very satisfied with the final report and thank you for taking the extra effort to customize the report format. We will definitely use your lab for future projects.

Program Manager, California

It has been a pleasure working with you and your team. The project was carried out to the highest standard and delivered in a timely manner. I will definitely recommend Avance Biosciences™’ services to colleagues and friends.

Senior Scientist, Singapore

When you partner with Avance Biosciences™, you gain a CRO partner that is creative, collaborative and dedicated to sound science with a focus on the regulatory requirements our partners require. Contact our technical staff to discuss how we can support you in your project!


Dedication to Quality

Dedication To Quality

The Avance Biosciences™ team is committed to strict adherence to CGMP and GLP regulations enacted by the US, European, Japanese, and other international regulatory agencies.


Extensive Experience

Open Communication

Our team has extensive knowledge and experience working with scientists, QA/QC professionals, and project managers from over 100 pharmaceutical and biotechnology companies and organizations throughout the world.


Open Communication

Open Communication

Transparency and integrity are two of our core values. Our well-trained, friendly, and professional study directors and project managers strive to complete your projects on-time with open communication channels and to your specifications.


Cutting Edge Science

Open Communication

Avance Biosciences™’ CGMP/GLP compliant genomic and microbial assays make use of the advanced technologies including real-time PCR, ddPCR, Sanger sequencing, next-gen sequencing, Southern blot, and more.