Next-Generation Sequencing (NGS) Center of Excellence
Avance Biosciences’ NGS Center of Excellence is dedicated to delivering high-quality, CGMP/GLP-compliant sequencing solutions to support every stage of biopharmaceutical development, from discovery through clinical validation and testing.
Our mission is to unite advanced sequencing expertise to maximize efficiency, foster innovation, and provide cutting-edge support for drug development and manufacturing, ensuring we stay agile in a rapidly evolving industry.
Next-Gen and Third-Gen Sequencing Platforms
Equipped with leading platforms, including Illumina, PacBio, Oxford Nanopore, Element AVITI™, and 10x Genomics, we offer unmatched expertise in vector characterization, transgene expression, CRISPR analysis, biodistribution, and release testing. Our integrated approach ensures precise, reliable data to accelerate regulatory submissions, enhance product safety, and advance innovative therapies from research through commercialization.
Sequencing Services
DNA Sequencing
RNA Sequencing
Epigenome
Whole Genome Sequencing (WGS)
Poly(A) / Transcriptomics (RNA-seq)
Whole Genome Bisulfite
Exome Sequencing
Total RNA Sequencing
Reduced Representation Bisulfite
Targeted / PCR-based Sequencing
Single-Cell Gene Expression and Immune Profiling
Chromatin Immunoprecipitation (ChIP-seq)
Metagenomic Sequencing
Metatranscriptome Sequencing
RNA Immunoprecipitation
Plasmid/Vector Sequencing
Gene Therapy Vector Sequencing
Enzymatic Methyl
Digital Southern
Isoform Sequencing
Assay for Transposase-Accessible Chromatic (ATAC-Seq)
Integration Site Analysis
Long ncRNA Sequencing
Adventitious Agent Testing
mRNA-Based Therapy
Technical Information
Download our whitepaper on “Phage Testing of Bacterial Cultures” to understand the critical importance of mitigating phage contamination in biotech and pharmaceutical industries. Learn about the lytic and lysogenic life cycles of phages, their role in bacterial biology, and the challenges they pose to the biotech and pharmaceutical industries due to contamination. Phage presence in cultures can significantly skew results, posing challenges in bacterial identification and isolation...
Download our whitepaper on “Phage Testing of Bacterial Cultures” to understand the critical importance of mitigating phage contamination in biotech and pharmaceutical industries. Learn about the lytic and lysogenic life cycles of phages, their role in bacterial biology, and the challenges they pose to the biotech and pharmaceutical industries due to contamination. Phage presence in cultures can significantly skew results, posing challenges in bacterial identification and isolation...
Download our whitepaper on “Phage Testing of Bacterial Cultures” to understand the critical importance of mitigating phage contamination in biotech and pharmaceutical industries. Learn about the lytic and lysogenic life cycles of phages, their role in bacterial biology, and the challenges they pose to the biotech and pharmaceutical industries due to contamination. Phage presence in cultures can significantly skew results, posing challenges in bacterial identification and isolation...
Next- and third-generation sequencing are vital for GMP, GLP, and clinical applications, but data integrity challenges and 21 CFR Part 11 compliance require secure instruments, validated workflows, and robust audit trails...
Genome editing offers unprecedented precision, but off-target effects remain a key safety concern. GUIDE-Seq provides a high-throughput, genome-wide method to map CRISPR-Cas activity in living cells, enabling researchers to assess specificity and ensure safer gene-editing therapies...
