Lentivirus Testing Services
Lentivirus Testing Services
Lentiviruses are a type of retrovirus, a family of RNA viruses that can integrate their genetic material into the host cell’s DNA. They are characterized by their ability to infect both dividing and non-dividing cells, making them a versatile tool in various fields of biology and medicine.
About
Lentiviruses have gained significant attention due to their use in gene therapy and molecular biology research. They are commonly employed for gene delivery into target cells, allowing the introduction or modification of specific genes. Lentiviral vectors, which are modified forms of the virus, have become valuable tools for genetic manipulation, including gene knockdown or overexpression, as well as gene editing techniques like CRISPR/Cas9.
To meet the demands of this rapidly growing field, Avance Biosciences’ Lentivirus Quality Control Testing Services offer comprehensive solutions to deliver cutting-edge results with confidence.
Key Lentivirus Product Support Services
Critical Quality Attributes
Assay
Description
Cell-based assay
Develop cell-based assay for evaluating post-transduction endpoint (mRNA expression, protein production)
Technical Information
This case study details how Avance Biosciences qualified an LC-MS/MS potency assay for a lentiviral gene therapy vector, measuring percent metabolite reduction in transduced patient-derived cells. The method met precision, assay performance, and system suitability criteria across two analysts and two days under a pre-approved cGMP protocol...
